Search results for "Contour length"

showing 3 items of 3 documents

Automated detection of protein unfolding events in atomic force microscopy force curves

2016

Atomic force microscopy is not only a high-resolution imaging device but also a mechanical machine, which can be used either to indent or stretch (soft) biomaterials. Due to the statistical nature of such materials (i.e., hydrogels or polymers) hundreds of force-distance curves are required to describe their mechanical properties. In this manuscript, we present an automated system for polymer unfolding detection based on continuous wavelet analysis. We have tested the automated program on elastin, which is an important protein that provides elasticity to tissues and organs. Our results show that elastin changes its mechanical behavior in the presence of electrolytes. In particular, we show …

0301 basic medicinechemistry.chemical_classificationHistologyMaterials sciencebiologyAtomic force microscopy0206 medical engineeringNanotechnology02 engineering and technologyPolymerAdhesion020601 biomedical engineeringForce curves03 medical and health sciencesMedical Laboratory Technology030104 developmental biologychemistrySelf-healing hydrogelsbiology.proteinContour lengthAnatomyElasticity (economics)Biological systemInstrumentationElastinMicroscopy Research and Technique
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Linear Dimensions of Adsorbed Semiflexible Polymers: What can be learned about their persistence length?

2019

Conformations of partially or fully adsorbed semiflexible polymer chains are studied varying both contour length $L$, chain stiffness, $\ensuremath{\kappa}$, and the strength of the adsorption potential over a wide range. Molecular dynamics simulations show that partially adsorbed chains (with ``tails,'' surface attached ``trains,'' and ``loops'') are not described by the Kratky-Porod wormlike chain model. The crossover of the persistence length from its three-dimensional value (${\ensuremath{\ell}}_{p}$) to the enhanced value in two dimensions ($2{\ensuremath{\ell}}_{p}$) is analyzed, and excluded volume effects are identified for $L\ensuremath{\gg}{\ensuremath{\ell}}_{p}$. Consequences fo…

Physicschemistry.chemical_classificationPersistence lengthGeneral Physics and AstronomyFOS: Physical sciencesPolymerCondensed Matter - Soft Condensed MatterSurface (topology)01 natural sciencesMolecular physicsCondensed Matter::Soft Condensed MatterMolecular dynamicsAdsorptionchemistryChain (algebraic topology)0103 physical sciencesExcluded volumeContour lengthSoft Condensed Matter (cond-mat.soft)010306 general physics
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A Monte Carlo Study of Living Polymers in 2D: Effect of Small Chains on Static Properties

1996

A slithering snake algorithm is combined with a binding and breaking chain algorithm to simulate the static behavior of living polymers according to Cates' description. It is shown that this simple two-dimensional simulation on a square lattice gives good agreement with the mean field theory. However, the large amount of small contour length chains for small values of the mean average length 〈L 〉 appears to be one of the reasons for the discrepancies observed between the simulated results and the mean field theory. This finding could explain disagreements between experimental observation and theory. Also, the results are not in favor of a swelling of the greater chains by the smaller one.

chemistry.chemical_classificationPhysicsPhysics and Astronomy (miscellaneous)Monte Carlo methodGeneral EngineeringPolymerSquare latticeAtomic and Molecular Physics and OpticschemistryChain (algebraic topology)Mean field theoryContour lengthStatistical physicsStatic behaviorArithmetic meanJournal de Physique II
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